It's best to limit painkillers to only when absolutely needed and not to make them a go to as they come loaded with side effects which may not manifest immediately. Most painkillers do not go well with alcohol or even red wines (Painkiller Addiction) » more Painkillers come with different side effects from depression to hormonal imbalance, nausea, constipation and more when abused Painkillers are drugs used to treat pain and they come in different ones (as well different brands) to treat different types of pain. A lot of people see painkillers as a part of daily/a way of life sadly and they've been abused (the use of painkillers) overtime and this remains a source of concern (albeit globally). Painkillers » more Painkillers come with different side effects from depression to hormonal imbalance, nausea, constipation and more when abused (Time) When not prescribed or when not absolutely necessary, painkillers should be ditched and here are reasons to: «1. Numerous Side Effects Painkillers come with different side effects from depression, hormonal imbalance, nausea, constipation, weakened immune system as well as liver and kidney damage amongst others. It's best to limit painkillers to only when absolutely needed and not to make them a go to as they come loaded with side effects which may not manifest immediately. «2. They are addictive Painkillers can become a habit! A lot of people have battled with addiction to painkillers with some already taken so much that it almost doesn't work for them anymore (these people go ahead to take over dose which comes with a lot of health risk) «3. Could be a deadly mix Most painkillers do not go well with alcohol or even red wines. A mixture of painkillers and any form of alcohol can result in nervous disorder, heavy breathing and other signs that can be fatal. Painkillers Most painkillers do not go well with alcohol or even red wines (Painkiller Addiction) «4. Some over-the-counter painkillers don't work Some over-the-counter painkillers actually don't work especially for more serious pains - not even increasing the dose helps- it's best to get prescription from a health practitioner and not abuse it. «5. Stick to the recommended dose As with all other drugs, painkillers should not be abused. Stick to doctor's prescribed dose and don't go overboard or take an over dose as this can be deadly.